产品详情
c-Abl Antibody
- 产品名称：c-Abl Antibody
- 产品型号：abx011619
- 产品厂商：Abbexa
- 产品文档：
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简单介绍
c-Abl Antibody
c-Abl Antibody
的详细介绍
c-Abl Antibody detects endogenous levels of total c-Abl. The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene.
| Target | c-Abl |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Tested Applications | WB, IHC |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | A synthesized peptide derived from human c-Abl. |
| Purification | Immunogen affinity purified. |
| Conjugation | Unconjugated |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight | 55 kDa |
| Swiss Prot | P00519 |
| Enzyme Commission Number | EC 2.7.10.2 |
| Buffer | Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |