PDGFR Antibody

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]. This antibody is supplied as crude ascites.

Target	PDGFR
Reactivity	Mouse
Host	Mouse
Clonality	Monoclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human PDGFR.
Purification	Mouse Monoclonal Antibody (Mab) supplied as crude ascites.
Isotype	IgG1κ
Conjugation	Unconjugated
Specificity	Purified His-tagged PDGFR protein (Fragment) was used to produced this monoclonal antibody.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P09619
Buffer	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.