TAP2 Antibody

TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transportersABC proteins transport various molecules across extra- and intra-cellular membranesABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)This protein is a member of the MDR/TAP subfamilyMembers of the MDR/TAP subfamily are involved in multidrug resistanceThis gene is located 7 kb telomeric to gene family member ABCB2The protein encoded by this gene is involved in antigen presentationThis protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulumMutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac diseaseAlternative splicing of this gene produces two products which differ in peptide selectivity and level of restoRation of surface expression of MHC class I molecules.

Target	TAP2
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human TAP2.
Purification	Affinity purified.
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	Q03519
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.