产品详情
NYREN18 Antibody
- 产品名称:NYREN18 Antibody
- 产品型号:abx011293
- 产品厂商:Abbexa
- 产品文档:
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简单介绍
NYREN18 Antibody
NYREN18 Antibody
的详细介绍
NYREN18 antibody detects endogenous levels of total NYREN18. NYREN18 Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. Induced by beta and gamma interferons. Directly interacts with NEDD8 and PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
| Target | NYREN18 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Tested Applications | WB, IHC |
| Recommended dilutions | WB: 1/500 - 1/3000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | A synthesized peptide derived from human NYREN18. |
| Purification | Affinity Chromatography. |
| Conjugation | Unconjugated |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight | 70 kDa |
| Swiss Prot | Q9Y5A7 |
| Buffer | Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |