CD44 Antibody

CD44, also known as IN, LHRMIC4, CDW44, HCELL.It is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration.It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs).This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis.Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Target	CD44
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Purified recombinant fragment of human CD44 (628-699) expressed in E. coli.
Isotype	IgG1
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	82 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.