产品详情
CD45RA Antibody (CF-Blue)
- 产品名称：CD45RA Antibody (CF-Blue)
- 产品型号：abx200328
- 产品厂商：Abbexa
- 产品文档：
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简单介绍
CD45RA Antibody (CF-Blue)
CD45RA Antibody (CF-Blue)
的详细介绍
Human CD45RA is expressed on all cells of hematopoietic origin, except erythrocytes. CD45RA is a transmembrane tyrosine phosphate which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RA isoform predominates on naive/resting T cells and medullary thymocytes.
| Target | CD45RA |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Tested Applications | FCM |
| Recommended dilutions | FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | Tissue / cell preparation (Human). Fresh human lymph node lymphocytes depleted of surface immunoglobulin positive cells were used as the immunogen. This antigen is a single chain glycoprotein which is expressed on B cells, monocytes, and T cell subsets. |
| Purification | Affinity Chromatography |
| Form | Liquid |
| Isotype | IgG1 |
| Conjugation | CF-Blue |
| Specificity | The HI100 monoclonal antibody reacts with human CD45RA, a 220 kDa molecule expressed by subpopulations of CD4+ peripheral Tlymphocytes, CD8+ peripheral T lymphocytes, and B cells. The CD45RA+ T cell populations are mainly naive/virgin allowing the use of HI100mAb as a phenotypic marker to discriminate T cell subsets. |
| Storage | Store in the dark at 2-8 °C. |
| Molecular Weight | 220 kDa |
| Swiss Prot | P08575 |
| GeneID | 5788 |
| Enzyme Commission Number | EC 3.1.3.4 |
| Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
| Availability | Shipped within 3-5 working days. |
| Note | This product is for research use only. |