C5 Protein
- 产品名称：C5 Protein
- 产品型号：A403
- 产品厂商：Quidel
- 产品文档：
C5 Protein
的详细介绍
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产品介绍 |
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| 品名 |
C5 Protein |
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| 货号 |
A403 |
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| 规格 |
250 µL/vial |
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| 浓度 |
1.0 mg/mL |
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| 纯度 |
> 90% |
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缓冲液 |
PBS |
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| 储存 |
At or below –70°C |
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| 产品描述 |
Purified human complement component C5. Complement component C5 is unique to the terminal complement pathway. 190 kD C5 protein is comprised of two chains (α 115 kD; ß 75 kD) and is present in plasma at 70 mg/L. Activation of either complement pathway can generate a C5 convertase enzyme capable of cleaving C5 to C5a (a potent anaphylatoxin) and C5b. Together with the other proteins of the terminal pathway, C5b forms the membrane attack complex or MAC. All Quidel complement components are tested for functional activity in a standard lytic or applicable functional ***** and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.
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| 参考资料 |
Nicholson-Weller, Butko, P, Wessels, M. Role of Complement Component C1q in IgG Independent Opsonophagocytosis of Group B Streptococcus, J. Immunol 163:2761-2768, 1999. Barbashov, S., Wang C. Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997. Koski, C., Dashell, S. Sublytic terminal complement complex decreases Po gene expression in schwan cells, J Neurochem 73(6):2321-2330, 1999. |
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| 使用说明 |
For Research Use Only. Not for use in diagnostic procedures. |
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