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Monoclonal Antibody to Human C6

  • 产品名称:Monoclonal Antibody to Human C6
  • 产品型号: A219
  • 产品厂商:Quidel
  • 产品文档:
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简单介绍
品牌:Quidel 货号:A219 品名:Monoclonal Antibody to Human C6 规格:100 µL

Monoclonal Antibody to Human C6

的详细介绍

产品介绍

品名

Monoclonal Antibody to Human C6

货号

A219 

规格

100 µL

 同种型

IgG1k

蛋白质浓度

> 1.0 mg/mL

纯度

≥ 95% by SDS PAGE

缓冲液

Borate Buffered Saline (pH 8.4 ± 0.2)

物种交叉反应

Human, baboon, Cynomolgus macaque, Rhesus macaque.

储存

≤ 30 Days 2-8˚C 

> 30 Days ≤ –20˚C

使用说明

For Research Use Only. Not for use in diagnostic procedures

产品描述

A murine monoclonal antibody to an epitope on C6 protein.

This monoclonal antibody was raised against purified human C. It is specific for an antigen expressed both on the native C6 molecule as well as on C6 in the MAC. It will not inhibit lysis of EA and will bind to MAC bound to a membrane.

Quidel's C6 monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry

特异性

The specificity of the monoclonal antibody for Complement protein, C6 was established by ELISA and radioimmuno***** (RIA). The antibody was also shown to bind isolated SC5b-9 and complement-lysed rabbit erythrocyte ghosts by indirect immunofluorescence. 

应用

参考资料

1、Thorgersen, EB. et al. Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood. Infect Immun. 77(2):725-732 (2002). 

2、Plested, JS. and Granoff, DM. Vaccine-induced opsonophagocytic immunity to Neisseria meningitidis group B. Clin Vaccine Immunol. 15(5):799- 804 (2008). 

3、Ragupathi, G. et al. Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity . J Immunol. 174(9):5706-5712 (2005). 

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