Monoclonal Antibody to Human C6
- 产品名称:Monoclonal Antibody to Human C6
- 产品型号: A219
- 产品厂商:Quidel
- 产品文档:
Monoclonal Antibody to Human C6
的详细介绍
产品介绍
Monoclonal Antibody to Human C6
A219
100 µL
IgG1k
> 1.0 mg/mL
≥ 95% by SDS PAGE
Borate Buffered Saline (pH 8.4 ± 0.2)
Human, baboon, Cynomolgus macaque, Rhesus macaque.
≤ 30 Days 2-8˚C
> 30 Days ≤ –20˚C
For Research Use Only. Not for use in diagnostic procedures
A murine monoclonal antibody to an epitope on C6 protein.
This monoclonal antibody was raised against purified human C. It is specific for an antigen expressed both on the native C6 molecule as well as on C6 in the MAC. It will not inhibit lysis of EA and will bind to MAC bound to a membrane.
Quidel's C6 monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry
The specificity of the monoclonal antibody for Complement protein, C6 was established by ELISA and radioimmuno***** (RIA). The antibody was also shown to bind isolated SC5b-9 and complement-lysed rabbit erythrocyte ghosts by indirect immunofluorescence.
1、Thorgersen, EB. et al. Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood. Infect Immun. 77(2):725-732 (2002).
2、Plested, JS. and Granoff, DM. Vaccine-induced opsonophagocytic immunity to Neisseria meningitidis group B. Clin Vaccine Immunol. 15(5):799- 804 (2008).
3、Ragupathi, G. et al. Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity . J Immunol. 174(9):5706-5712 (2005).
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