C4 Monoclonal Antibody to Human C4 Binding Protein
- 产品名称:C4 Monoclonal Antibody to Human C4 Binding Protein
- 产品型号: A215
- 产品厂商:Quidel
- 产品文档:
C4 Monoclonal Antibody to Human C4 Binding Protein
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产品介绍
C4 Monoclonal Antibody to Human C4 Binding Protein
A215
100 µL
IgG2bK
> 1.0 mg/mL
Borate Buffered Saline (pH 8.4 ± 0.2)
Human, baboon
≤ 30 Days 2-8˚C > 30 Days ≤ –20˚C
For Research Use Only. Not for use in diagnostic procedures
A murine monoclonal antibody to an epitope on C4 Binding Protein.
This monoclonal antibody was raised against purified human C4 Binding Protein.
Quidel's C4 Binding Protein monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry.
The specificity of the monoclonal antibody was established via a series of immunoassays. First, the antibody was shown by ELISA to bind purified C4 Binding Protein (C4BP) immobilized in microtiter wells. Second, free (unbound) C4BP and human serum were shown via inhibition EIA to inhibit the binding of this antibody to immobilized C4BP. Other complement proteins, including C4, did not inhbit binding
1、Roos, A. et al. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol 17:1724-1734 (2006).
2、 Grosskinsky, S. et al. Human complement regulators C4b-Binding Protein and C1 Esterase Inhibitor interact with a novel outer surface protein of Borrelia recurrentis. PLOS Neglected Tropical Diseases 4(6):e698 (2010)
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